Recurrent miscarriage: a defect in nature's quality control?
نویسندگان
چکیده
منابع مشابه
Balanced Reciprocal Translocation in A Case of Recurrent Miscarriage
Reciprocal translocation carriers have reduced fertility, increased risk of spontaneous abortion or unbalanced karyotype in their offspring. Here, we report the inheritance of a translocation between chromosomes 12 and 16 in a family with a history of five consecutive blighted ova and an offspring with three cell lines of different genotypes. We assessed parental karyotypes and identified a het...
متن کاملRecurrent miscarriage
Recurrent miscarriages are one or more pregnancy losses before 20-24 weeks of gestation or below a fetal weight of 500 g (Pic. 1). About 1% of women in reproductive age are affected by recurrent miscarriages. The majority of patients are counseled to try to conceive again, and chances are about 60% that the next pregnancy is successful without treatment. However, each additional loss worsens th...
متن کاملRecurrent miscarriage
Recurrent miscarriages are one or more pregnancy losses before 20-24 weeks of gestation or below a fetal weight of 500 g (Pic. 1). About 1% of women in reproductive age are affected by recurrent miscarriages. The majority of patients are counseled to try to conceive again, and chances are about 60% that the next pregnancy is successful without treatment. However, each additional loss worsens th...
متن کاملRecurrent miscarriage
Miscarriage is one of the most common complications of pregnancy. Fifteen percent of clinically recognized pregnancies end in miscarriage. The major cause of spontaneous miscarriage is genetic or developmental abnormalities of the foetus. Recurrent miscarriage occurs in 3% of the population and has been associated with thrombophillias, infections and endocrine, anatomical and immune factors. Tr...
متن کاملSubtelomeric Rearrangements in Patients with Recurrent Miscarriage
Objective The Subtelomeric rearrangements are increasingly being investigated in cases of idiopathic intellectual disabilities (ID) and congenital abnormalities (CA) but have also been suspected to be responsible for unexplained recurrent miscarriage (RM). We have noticed a higher risk of subtelomeric translocations in association with CA and ID. Such rearrangements can go unnoticed through con...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2002
ISSN: 1460-2350
DOI: 10.1093/humrep/17.8.1959